Turmeric is a natural antibiotic with anti-inflammatory and antioxidant properties. It can aid digestive issues, joint pain and allergies as well as reduce blood lipid levels and improve glycemic control.
Curcumin has been found to produce changes on a molecular level that could potentially help prevent and treat some forms of cancer, while also helping protect against Alzheimer’s and other neurodegenerative conditions.
Anti-inflammatory
Curcumin can help combat chronic inflammation by suppressing multiple molecules involved in the inflammatory process and acting as an antioxidant to protect cells against oxidative damage.
Studies have demonstrated that supplementing with turmeric or curcumin can significantly alleviate pain and enhance quality of life for those living with RA. One possible explanation could be its ability to increase nitric oxide (NO) levels in the blood, thus decreasing inflammation while improving circulation and increasing blood flow.
Curcumin also boasts anti-inflammatory benefits in the prostate gland, where its application has been shown to lower levels of prostate-specific antigen (PSA), decrease urination frequency and urgency, improve overall quality of life and can even stop cancer cell growth or induce tumorous cell death.
Curcumin can prevent epithelial-mesenchymal transition (EMT), where cancerous cells lose their polarity and acquire the ability to migrate and disseminate, by upregulating E-cadherin and g-catenin levels while simultaneously downregulating vimentin in breast cancer cells. Furthermore, it inhibits NF-kB/Snail signaling which plays an active role in lipopolysaccharide-induced EMT.
Anti-tumor
Curcumin has been shown in numerous research studies to both kill cancer cells and stop them from growing, but most were conducted in laboratory settings or with animals; their relevance is uncertain in human circumstances and additional research needs to be conducted before making definitive statements about whether curcumin can prevent and treat cancer in people.
Curcumin can stop tumor growth by disrupting several of the signaling pathways responsible for cancer progression and treatment resistance. Furthermore, curcumin induces programmed cell death (apoptosis) in cancer cells while increasing expression of anti-metastasis proteins.
Curcumin can effectively inhibit the proliferation of hematological cancers such as leukemia and lymphoma by blocking activation of proinflammatory transcription factor NF-kB and suppressing IkBa phosphorylation and DNA binding; while also upregulating proapoptotic protein BIM. Furthermore, curcumin reduced lipid peroxidation in human colorectal cancer cells while simultaneously increasing glutathione content – both feats accomplished with just one supplement!
Anti-cancer
Laboratory and animal studies indicate that curcumin may help stop or slow the spread of certain cancers. Furthermore, it could improve chemotherapy’s efficacy as studies are ongoing.
Curcumin disrupts several molecular pathways associated with cancer development and inflammation responses, inhibiting NF-kappa B activation while suppressing production of pro-inflammatory molecules like cytokines, chemokines, adhesion molecules, and genes involved with cell proliferation, adhesion and survival. Furthermore, curcumin blocks enzymes involved with creating oxidative stress such as cyclooxygenase and inducible nitric oxide synthase from acting.
Cancer cell lines treated with this therapy undergo apoptosis, or programmed cell death, prompting them to stop growing out of control and die instead. Furthermore, this therapy reduces activity from proteins responsible for resistance against treatment with certain drugs.
Studies are underway to see whether turmeric can aid in the prevention or treatment of various forms of cancer, specifically prostate, pancreatic, breast, lung and stomach cancers. Preliminary results suggest it might protect against prostate cancer while improving chemotherapy treatments for pancreatic and keeping breast cancers from recurring post-treatment. Furthermore, research is looking into its ability to mitigate side effects associated with cancer therapy treatments as well.
Anti-diabetic
Researchers believe curcumin may help delay or prevent type 2 diabetes. Curcumin enhances beta cells’ production of insulin for energy transportation to cells. Curcumin also decreases insulin resistance and oxidative stress in people with prediabetes while simultaneously decreasing blood sugar levels for those living with type 1 diabetes.
By strengthening endothelium – which lines your blood vessels – it helps reduce oxidative stress and inflammation that contributes to heart disease, as well as increase brain-derived neurotrophic factor (BDNF), helping improve memory retention and learning abilities.
Studies involving human subjects are more limited, however a clinical trial in 2012 demonstrated significant improvements for those with pre-diabetes who took turmeric capsules for nine months as part of a therapeutic intervention to manage fasting blood sugar and A1c levels. Curcumin may enhance Metformin’s effectiveness by improving insulin sensitivity, suppressing G6Pase and PEPCK enzyme activity and lowering elevated triglyceride levels as well as decreasing inflammation and oxidative stress levels.
Anti-bacterial
Researchers have recently demonstrated the antibacterial properties of curcumin. It has been demonstrated to inhibit bacterial growth while increasing antibiotic effectiveness; one recent study demonstrated this fact by showing how curcumin combined with amoxicillin had greater effectiveness than either treatment alone. Furthermore, another recent study concluded that curcumin attenuated exercise-induced muscle soreness among healthy subjects; an important finding which shows its benefits extend far beyond those already living with health conditions.
Curcumin can help to mitigate inflammation and oxidative damage to cells, serving as both a free radical scavenger and hydrogen donor. Furthermore, it binds to transitional metals like iron and copper while inhibiting activation of proinflammatory enzymes; additionally, modulating transcription factors and signaling pathways is another benefit of taking curcumin daily.
Curcumin is poorly absorbed in the body, so it must be taken orally for optimal absorption. Researchers have developed strategies for increasing its bioavailability; such as coupling it to peptide carriers or encasing it within polylactic-co-glycolic acid micelle nanoparticles to increase bioavailability and improve absorption rates in the body. These methods enhance its absorption rate as well as bioavailability in this way.
Anti-fungal
Internet resources abound with information on this humble, brightly-hued spice and its many healing properties, while elite print media, like the New York Times or Wall Street Journal have highlighted them all to highlight this edible hero’s advantages.
Curcumin has proven its antibacterial effectiveness by permeating bacteria cell membranes and inhibiting protein synthesis [46]. Furthermore, curcumin exhibits synergy when combined with antibiotic drugs like Doxycycline, Polymyxin B or Erythromycin for greater effectiveness [48-50].
Curcumin has shown to possess broad-spectrum antibiotic activity against Gram-positive and Gram-negative bacteria, such as A. baumannii, E. coli, Enterococcus spp., Helicobacter pylori, K. pneumoniae and P. aeruginosa. It does so through inhibiting their virulence factors, biofilm formation and oxidative stress mechanisms.
Curcumin is widely recognized for its ability to neutralize free radicals, activating GSH receptors and increasing catalase and SOD enzyme activities. Furthermore, when combined with other antioxidants such as piperine it exhibits synergistic action which enhances its efficacy while increasing bioavailability.
Anti-viral
Curcumin has been proven to inhibit multiple viruses through multiple mechanisms. It can prevent viral infections directly by interfering with their replication machinery and by suppressing essential viral replication pathways such as PI3K/Akt and NF-kB signaling pathways.
Recent research has demonstrated that curcumin can significantly lower EV71 infection in human intestinal epithelial cells by stabilizing pathogen-containing vacuolar membranes and preventing cytosolic relocation of lysosomal proteins towards apoptosis (Marathe et al., 2012). Furthermore, PKCd activation is key for entry of EV71 into cells; curcumin has been demonstrated to inhibit this phosphorylation 100 fold or more efficiently than before!
Preserva Wellness’s Immunoblast Juice and Immune Boosting Tea provide excellent ways of taking turmeric for health purposes on a regular basis, providing 95% pure turmeric powder combined with other natural ingredients proven to support immune health while protecting against viral infections like colds and flu.
Anti-aging
Curcumin provides multiple anti-aging benefits. It can slow the aging process by inhibiting cancer cell growth and increasing healthy cell reproduction, as well as protecting against oxidative damage by activating antioxidant enzymes and suppressing molecules that promote inflammation.
Turmeric may help slow aging by increasing levels of brain-derived neurotrophic factor (BDNF). This protein works to keep neurons healthy while also regulating communication between nerve cells, essential for memory and learning. Common brain diseases like Alzheimer’s are linked to decreased levels of BDNF; studies on animals indicate curcumin can boost these levels and prevent or reverse some forms of dementia.
Curcumin can help improve endothelial function, the health of blood vessel walls and heart tissue. This can result in reduced blood pressure and risk for cardiovascular disease, improved energy levels and decreased fatigue; plus it helps protect against glycation – when sugars bind with proteins and fats in your body to cause cell dysfunction and hasten aging processes.





Recent Comments